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Differences in the intrinsic chondrogenic potential of human mesenchymal stromal cells and iPSC‐derived multipotent cells

Abstract Background Human multipotent progenitor cells (hiMPCs) created from induced pluripotent stem cells (iPSCs) represent a new cell source for cartilage regeneration. In most studies, bone morphogenetic proteins (BMPs) are needed to enhance transforming growth factor‐β (TGFβ)‐induced hiMPC chon...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Shiqi Xiang, Zixuan Lin, Meagan J. Makarcyzk, Kanyakorn Riewruja, Yiqian Zhang, Xiurui Zhang, Zhong Li, Karen L. Clark, Eileen Li, Silvia Liu, Tingjun Hao, Madalyn R. Fritch, Peter G. Alexander, Hang Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2022-12-01
Schriftenreihe:Clinical and Translational Medicine
Schlagworte:
cartilage regeneration
chondrocyte hypertrophy
chondrogenesis
induced pluripotent stem cells
mesenchymal stromal cells
Smad
Online-Zugang:https://doi.org/10.1002/ctm2.1112
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