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Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites

Gasdermins (GSDMs) are a group of proteins that are cleaved by inflammatory caspases to induce pore formation in the plasma membrane to cause membrane permeabilization and lytic cell death or pyroptosis. All GSDMs share a conserved structure, containing a cytotoxic N-terminal (NT) pore-forming domai...

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Principais autores: Shanshan Wang, France Moreau, Kris Chadee
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2022-06-01
סדרה:Frontiers in Immunology
נושאים:
gasdermin
parasite
macrophage
Entamoba histolytica
innate immunity
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2022.900553/full
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