ZRC3308 Monoclonal Antibody Cocktail Shows Protective Efficacy in Syrian Hamsters against SARS-CoV-2 Infection

We have developed a monoclonal antibody (mAb) cocktail (ZRC-3308) comprising of ZRC3308-A7 and ZRC3308-B10 in the ratio 1:1 for COVID-19 treatment. The mAbs were designed to have reduced immune effector functions and increased circulation half-life. mAbs showed good binding affinities to non-competi...

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Autors principals:	Pragya D. Yadav, Sanjeev Kumar Mendiratta, Sreelekshmy Mohandas, Arun K. Singh, Priya Abraham, Anita Shete, Sanjay Bandyopadhyay, Sanjay Kumar, Aashini Parikh, Pankaj Kalita, Vibhuti Sharma, Hardik Pandya, Chirag G. Patel, Mihir Patel, Swagat Soni, Suresh Giri, Mukul Jain
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-12-01
Col·lecció:	Viruses
Matèries:	ZRC3308 SARS-CoV-2 monoclonal antibody prophylaxis hamsters
Accés en línia:	https://www.mdpi.com/1999-4915/13/12/2424
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