Therapeutic inhibition of MPO stabilizes pre-existing high risk atherosclerotic plaque

Currently there are no established therapies to treat high-risk patients with unstable atherosclerotic lesions that are prone to rupture and can result in thrombosis, abrupt arterial occlusion, and a precipitous infarction. Rather than being stenotic, rupture-prone non-occlusive plaques are commonly...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Weiyu Chen, Sergey Tumanov, Stephanie M.Y. Kong, David Cheng, Erik Michaëlsson, André Bongers, Carl Power, Anita Ayer, Roland Stocker
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-12-01
coleção:	Redox Biology
Assuntos:	Atherosclerosis Unstable plaque Myeloperoxidase (MPO) Myeloperoxidase inhibitor AZM198 Magnetic resonance imaging (MRI)
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231722003044
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!