Recombinant trimeric HA protein immunogenicity of H5N1 avian influenza viruses and their combined use with inactivated or adenovirus vaccines.

BACKGROUND: The highly pathogenic avian influenza (HPAI) H5N1 virus continues to cause disease in poultry and humans. The hemagglutinin (HA) envelope protein is the primary target for subunit vaccine development. METHODOLOGY/PRINCIPAL FINDINGS: We used baculovirus-insect cell expression to obtain tr...

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Detalhes bibliográficos

Principais autores:	Shih-Chang Lin, Ming-Hsi Huang, Pei-Chun Tsou, Li-Min Huang, Pele Chong, Suh-Chin Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-01-01
Colecção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3104987?pdf=render
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