Protective effect of kaempferol glucoside against lipopolysaccharide-caused acute lung injury via targeting Nrf2/NF-κB/NLRP3/GSDMD: Integrating experimental and computational studies

The current study explored the protective potential of kaempferol 3-sophoroside-7-glucoside (KSG) against acute lung injury (ALI). Pre-treatment with KSG effectively secured mice from ALI and showed similar efficaciousness to dexamethasone. KSG markedly increased the survival rate and alleviated lun...

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Autori principali:	Wesam H. Abdulaal, Ulfat M. Omar, Mustafa Zeyadi, Dina S. El-Agamy, Nabil A. Alhakamy, Naif A. R. Almalki, Hani Z. Asfour, Mohammed W. Al-Rabia, Abdulrahim A. Alzain, Gamal A. Mohamed, Sabrin R.M. Ibrahim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2024-06-01
Serie:	Saudi Pharmaceutical Journal
Soggetti:	Acute lung injury Computational studies Health and wellbeing Industrial development Kaempferol 3-sophoroside-7-glucoside Life on land
Accesso online:	http://www.sciencedirect.com/science/article/pii/S1319016424001233
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