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Pangenome-Guided Reverse Vaccinology and Immunoinformatics Approach for Rational Design of a Multi-Epitope Subunit Vaccine Candidate Against the Multidrug-Resistant Pathogen <i>Chromobacterium violaceum</i>: A Computational Immunopharmacology Perspective

<b>Background</b>: <i>Chromobacterium violaceum</i> is an emerging multidrug-resistant (MDR) Gram-negative bacterium associated with severe septicemia, abscess formation, and high mortality, particularly in immunocompromised individuals. Increasing antimicrobial resistance and the absence of approve...

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Hovedforfatter: Khaled S. Allemailem
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-12-01
Serier:Pharmaceuticals
Fag:
<i>Chromobacterium violaceum</i>
multi-epitope vaccine
pangenome
multidrug resistance
reverse vaccinology
subtractive proteomics
Online adgang:https://www.mdpi.com/1424-8247/19/1/29
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