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The glucose-6-phosphatase system in cancer: from endoplasmic reticulum glucose-6-phosphate flux to stemness, immune escape, and therapeutic vulnerability

The endoplasmic reticulum glucose-6-phosphatase (G6Pase) system, traditionally linked to hepatic and renal glucose homeostasis, is increasingly recognized as a regulator of intracellular glucose-6-phosphate (G6P) partitioning with broad relevance to cancer biology. Emerging evidence implicates its c...

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Principais autores: Bogdan Alexandru Danalache, Abdallah Fallah, Frédéric Mercier, Borhane Annabi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-07-01
Serija:Frontiers in Oncology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fonc.2026.1912198/full
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