Access to Axially Chiral Aryl Aldehydes via Carbene-Catalyzed Nitrile Formation and Desymmetrization Reaction

An approach utilizing N-heterocyclic carbene for nitrile formation and desymmetrization reaction is developed. The process involves kinetic resolution, with the axially chiral aryl monoaldehydes obtained in moderate yields with excellent optical purities. These axially chiral aryl monoaldehydes can...

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Detalhes bibliográficos

Principais autores:	Yuanlin Cai, Ya Lv, Liangzhen Shu, Zhichao Jin, Yonggui Robin Chi, Tingting Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Association for the Advancement of Science (AAAS) 2024-01-01
Colecção:	Research
Acesso em linha:	https://spj.science.org/doi/10.34133/research.0293
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