sTLR9 on maternal Circulating immune cells as a negative regulatory phenotype during pregnancy

Abstract TLR9 is an intracellular receptor that can also be localized to the cell surface, called sTLR9. sTLR9 is thought to have a negative immunomodulatory effect, which is conductive to the maintenance of immune tolerance. Since pregnancy is a physiological process accompanied with inflammation e...

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Autors principals:	Hong Wang, Wenting Lu, Mengru Zhu, Yongli Yu, Liying Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2025-08-01
Col·lecció:	Cellular and Molecular Life Sciences
Matèries:	Pregnant maternal immune response Surface toll-like receptor 9 (sTLR9)-expressing immune cells Peripheral white blood cells (PWBCs) Immune tolerance Inflammatory regulation
Accés en línia:	https://doi.org/10.1007/s00018-025-05858-8
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