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Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness

The goal of this study was to investigate how alterations in extracellular matrix (ECM) biophysical properties modulate corneal keratocyte phenotypes in response to specific wound healing cytokines and Rho GTPases. Rabbit corneal keratocytes were plated within standard collagen matrices (2.5 mg/...

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Bibliographic Details
Main Authors: W. Matthew Petroll, Neema Lakshman
Format: Artigo
Language:Inglês
Published: MDPI AG 2015-04-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:http://www.mdpi.com/2079-4983/6/2/222
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