Transcriptome analysis reveals therapeutic potential of NAMPT in protecting against abdominal aortic aneurysm in human and mouse

Abdominal Aortic Aneurysm (AAA) is a life-threatening vascular disease characterized by the weakening and ballooning of the abdominal aorta, which has no effective therapeutic approaches due to unclear molecular mechanisms. Using single-cell RNA sequencing, we analyzed the molecular profile of indiv...

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Detalhes bibliográficos

Principais autores:	Yu Ouyang, Yimei Hong, Cong Mai, Hangzhen Yang, Zicong Wu, Xiaoyan Gao, Weiyue Zeng, Xiaohui Deng, Baojuan Liu, Yuelin Zhang, Qingling Fu, Xiaojia Huang, Juli Liu, Xin Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2024-04-01
coleção:	Bioactive Materials
Assuntos:	Abdominal aorta Vascular smooth muscle cells Senescence Oxidative phosphorylation Electron transport chain
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452199X2300395X
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