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Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method

The new breakthrough cystic fibrosis (CF) drug combination of ivacaftor (IVA), tezacaftor (TEZ), and elexacaftor (ELX), namely “caftor” drugs, directly modulates the activity and trafficking of the defective CF transmembrane conductance regulator protein (CFTR) underlying the CF disease. The role of...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Federica Pigliasco, Alessia Cafaro, Manuela Stella, Giammarco Baiardi, Sebastiano Barco, Nicoletta Pedemonte, Claudia D’Orsi, Federico Cresta, Rosaria Casciaro, Carlo Castellani, Maria Grazia Calevo, Francesca Mattioli, Giuliana Cangemi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2023-02-01
Rangatū:Biomedicines
Ngā marau:
ivacaftor
tezacaftor
elexacaftor
CFTR
therapeutic drug monitoring
LC–MS/MS
Urunga tuihono:https://www.mdpi.com/2227-9059/11/2/628
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