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Enantioselective construction of ortho-sulfur- or nitrogen-substituted axially chiral biaryls and asymmetric synthesis of isoplagiochin D

Ortho-heteroatom-substituted axially chiral biaryls are valuable structures in synthetic and medicinal chemistry. Here, the authors established an efficient synthesis of these chiral structures via asymmetric cross-coupling.

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Autori principali: He Yang, Wenjun Tang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2022-08-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-022-32360-7
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