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Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides

Non-viral transfection reagents are continuously being developed in attempt to replace viral vectors. Among those non-viral vectors, dendrimers have gained increasing interest due to their unique molecular structure and multivalency. However, more improvements are still needed to achieve higher effi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Haneen Daralnakhla, Osama Saher, Susanna Zamolo, Safa Bazaz, Jeremy P. Bost, Marc Heitz, Karin E. Lundin, Samir EL Andaloussi, Tamis Darbre, Jean-Louis Reymond, Rula Zain, C. I. Edvard Smith
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-01-01
Schriftenreihe:Pharmaceutics
Schlagworte:
splice-switching oligonucleotide
gene therapy
lipophilic
peptide dendrimers
excipients
synergism
Online-Zugang:https://www.mdpi.com/1999-4923/13/1/116
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