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Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.

Capecitabine (CAP) is a 5-FU pro-drug approved for the treatment of several cancers and it is used in combination with gemcitabine (GEM) in the treatment of patients with pancreatic adenocarcinoma (PDAC). However, limited pre-clinical data of the effects of CAP in PDAC are available to support the u...

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Autori principali: Aurélie Courtin, Frances M Richards, Tashinga E Bapiro, Jo L Bramhall, Albrecht Neesse, Natalie Cook, Ben-Fillippo Krippendorff, David A Tuveson, Duncan I Jodrell
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0067330&type=printable
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