Potential utility of salivary gland amyloid uptake as a surrogate marker for adipose tissue and amyloid-beta dynamics based on its association with BMI and cerebral amyloid burden

Abstract Recent studies have noted an unexpected inverse correlation between body mass index (BMI) and cerebral amyloid-beta (Aβ) deposition, suggesting a potential involvement of adipose tissue in AD pathology. Given the adipose-rich nature of salivary glands, we investigated whether Aβ uptake in t...

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Autors principals:	Kyu Ri Kim, Kyungmin Kim, Ji-Young Kim, Hai-jeon Yoon
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-07-01
Col·lecció:	Scientific Reports
Matèries:	Alzheimer’s disease Amyloid PET Standardized uptake value ratio of salivary glands (SUVRSG) Body mass index Adipose tissue
Accés en línia:	https://doi.org/10.1038/s41598-025-11731-2
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