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Dexmedetomidine for opioid-sparing postoperative analgesia: a systematic review and meta-analysis

Abstract Introduction Postoperative opioid use is associated with adverse effects and increased risk of long-term dependence. Dexmedetomidine (Dex), a selective alpha-2 adrenergic agonist, has analgesic and sedative properties and may reduce opioid requirements when used perioperatively. This system...

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Autors principals: Yanli Sun, Yu Yao, Ying Li, Wei Deng
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-01-01
Col·lecció:BMC Anesthesiology
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Accés en línia:https://doi.org/10.1186/s12871-025-03606-w
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