Experimental Persistent Infection of BALB/c Mice with Small-Colony Variants of Burkholderia pseudomallei Leads to Concurrent Upregulation of PD-1 on T Cells and Skewed Th1 and Th17 Responses.

<h4>Background</h4>Burkholderia pseudomallei (B. pseudomallei), the causative agent of melioidosis, is a deadly pathogen endemic across parts of tropical South East Asia and Northern Australia. B. pseudomallei can remain latent within the intracellular compartment of the host cell over p...

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Hlavní autoři: Jia-Xiang See, Chandramathi Samudi, Alireza Saeidi, Nivedita Menon, Leang-Chung Choh, Jamuna Vadivelu, Esaki M Shankar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2016-03-01
Edice:PLoS Neglected Tropical Diseases
On-line přístup:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004503&type=printable
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