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Inhibition of immune checkpoints and Vascular Endothelial Growth Factor as combination therapy for cancer: an overview of rationale, preclinical evidence, and initial clinical data

The role of angiogenesis as a mediator of immune regulation in the tumor microenvironment has recently come into focus. Furthermore, emerging evidence indicates that immunotherapy can lead to immune-mediated vasculopathy in the tumor, suggesting that the tumor vasculature may be an important interfa...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Patrick Alexander Ott, F. Stephen eHodi, Elizabeth eBuchbinder
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2015-09-01
Rangatū:Frontiers in Oncology
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00202/full
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