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Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent

Abstract Human skin equivalents (HSEs) are a popular technology due to limitations in animal testing, particularly as they recapitulate aspects of structure and function of human skin. Many HSEs contain two basic cell types to model dermal and epidermal compartments, however this limits their applic...

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Main Authors: Kirsty Goncalves, Paola De Los Santos Gomez, Lydia Costello, Lucy Smith, Hugh Mead, Amy Simpson, Stefan Przyborski
Format: Artigo
Language:Inglês
Published: Wiley 2023-03-01
Series:Bioengineering & Translational Medicine
Subjects:
3D cell culture
epidermal structure
in vitro
melanocytes
pigmentation
skin model
Online Access:https://doi.org/10.1002/btm2.10415
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