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Functions and inhibitors of CHK1 in cancer therapy

CHK1 plays a crucial role in cancer biology as it modulates cell cycle checkpoint activation and DNA repair. Furthermore, a number of other cellular functions of CHK1 are also gradually discovered. Based on these biological functions, CHK1 has been regarded as a potential target for cancer therapy,...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Kailong Jiang, Minjie Deng, Wenjing Du, Tao Liu, Jia Li, Yubo Zhou
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2024-06-01
Rangatū:Medicine in Drug Discovery
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2590098624000101
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