Estrogen receptor α regulates SVCT2 protein level in human breast cancer cells

Abstract The solute carrier (SLC) protein family, traditionally recognized for transporting molecules across cell membranes, is gaining attention for its broader roles, including signaling. Among SLC proteins, the ascorbate transporter SVCT2 remains poorly understood, particularly in relation to est...

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Bibliografiska uppgifter
Huvudupphovsmän: Soon Young Jang, Eunbi Hong, Yebin Jo, Jiyun Kim, Jong-Ho Kim, Yuran Na, Chang-Hwan Yeom, Yoon Jung Yang, Emanuela Jacchetti, Manuela Teresa Raimondi, Seyeon Park
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Portfolio 2025-07-01
Serie:Scientific Reports
Ämnen:
SVCT2
Estrogen receptor alpha
Degradation
XIAP
Drug resistance
Breast cancer
Länkar:https://doi.org/10.1038/s41598-025-11758-5
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