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Functionalized Polymeric Microneedles for Transdermal Delivery of Ovalbumin Protein Antigen

<b>Background/Objectives:</b> Microneedles represent an innovative transdermal drug delivery approach, especially for protein antigens. This study aimed to develop a dual-functional, dissolvable microneedle system loaded with β-glucan and fucoidan in a hyaluronic acid matrix to achieve transdermal i...

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Principais autores: Yi Liu, Feng Tan, Decheng Zhao, Liwen Zhang, Nianni Zhang, Chengwei Bai, Ziyang Guo, Xiongjian Guan, Guanyu Chen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-06-01
coleção:Pharmaceutics
Assuntos:
dissolvable microneedles
transdermal drug delivery
immunomodulation
reactive oxygen species (ROS) regulation
β-glucan
fucoidan
Acesso em linha:https://www.mdpi.com/1999-4923/17/6/737
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