Modeling age-related methylation changes in vitro with intestinal organoids
Abstract Background Intestinal organoids, three-dimensional cultures derived from intestinal stem cells, serve as a promising model for studying aging. DNA methylation is recognized as a biological clock of aging, and we hypothesized the value of organoid DNA methylation for aging research. To test...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2026-03-01
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| Seria: | BMC Biology |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s12915-026-02558-y |
| Etykiety: |
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