Indirect Modeling of Post-Prandial Intestinal Lymphatic Uptake of Halofantrine Using PBPK Approaches: Limitations and Implications

<b>Background/Objectives:</b> Despite the recognized importance and distinctive characteristics of the intestinal lymphatic pathway in drug absorption, its pharmacokinetic modeling remains largely unexplored. This study aimed to address this gap by developing a physiologically based pharmacokinetic...

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Hlavní autoři:	Malaz Yousef, Farag E. S. Mosa, Khaled H. Barakat, Neal M. Davies, Raimar Löbenberg
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-09-01
Edice:	Pharmaceutics
Témata:	in silico PBPK lymphatic uptake halofantrine chylomicrons
On-line přístup:	https://www.mdpi.com/1999-4923/17/9/1228
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