Evidence for transcript-specific epigenetic regulation of glucocorticoid-stimulated skeletal muscle 11β-hydroxysteroid dehydrogenase-1 activity in type 2 diabetes
<p>Abstract</p> <p>Background</p> <p>The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) converts inactive cortisone into active cortisol in insulin target tissues. In people with type 2 diabetes, skeletal muscle (SkM) 11βHSD1 is upregulated by the potent glucocorticoid dexamethasone. The <...
Na minha lista:
| Principais autores: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2012-12-01
|
| coleção: | Clinical Epigenetics |
| Assuntos: | |
| Acesso em linha: | http://www.clinicalepigeneticsjournal.com/content/4/1/24 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|