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Primate-specific transposable elements shape transcriptional networks during human development

The human genome harbors more than 4.5 million transposable element (TE)-derived insertions, the result of recurrent waves of invasion and internal propagation. Here they show that TEs belonging to evolutionarily recent subfamilies go on to regulate later stages of human embryonic development, notab...

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Autors principals: Julien Pontis, Cyril Pulver, Christopher J. Playfoot, Evarist Planet, Delphine Grun, Sandra Offner, Julien Duc, Andrea Manfrin, Matthias P. Lutolf, Didier Trono
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2022-11-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-022-34800-w
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