Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution

Abstract Precise regulation of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses to pathogens. However, a global model integrating regulation and functional consequences of inflammation‐associated mRNA decay remains to be established. Using time‐resolved high‐resolution...

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Autors principals:	Vitaly Sedlyarov, Jörg Fallmann, Florian Ebner, Jakob Huemer, Lucy Sneezum, Masa Ivin, Kristina Kreiner, Andrea Tanzer, Claus Vogl, Ivo Hofacker, Pavel Kovarik
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer Nature 2016-05-01
Col·lecció:	Molecular Systems Biology
Matèries:	mRNA decay inflammation macrophage PAR‐CLIP
Accés en línia:	https://doi.org/10.15252/msb.20156628
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