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Genipin promotes the apoptosis and autophagy of neuroblastoma cells by suppressing the PI3K/AKT/mTOR pathway

Abstract This study investigated the underlying function and mechanism of genipin in neuroblastoma (NB). Using flow cytometry analysis and cytotoxicity tests, in vitro studies were conducted to assess the effects of genipin on the SK-N-SH cell line. The mechanism of action of genipin was explored th...

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Detalhes bibliográficos
Principais autores: Xinying Liu, Can Zhou, Boli Cheng, Yan Xiong, Qin Zhou, Enyu Wan, Yun He
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-08-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-024-71123-w
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