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Effects of spatiotemporal HSV-2 lesion dynamics and antiviral treatment on the risk of HIV-1 acquisition.

Patients with Herpes Simplex Virus-2 (HSV-2) infection face a significantly higher risk of contracting HIV-1. This is thought to be due to herpetic lesions serving as entry points for HIV-1 and tissue-resident CD4+ T cell counts increasing during HSV-2 lesional events. We have created a stochastic a...

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Autors principals: Catherine M Byrne, Soren Gantt, Daniel Coombs
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-04-01
Col·lecció:PLoS Computational Biology
Accés en línia:http://europepmc.org/articles/PMC5940244?pdf=render
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