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GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program.

The antagonistic actions of Polycomb and Trithorax are responsible for proper cell fate determination in mammalian tissues. In the epidermis, a self-renewing epithelium, previous work has shown that release from Polycomb repression only partially explains differentiation gene activation. We now show...

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Detalles Bibliográficos
Principais autores: Amelia Soto Hopkin, William Gordon, Rachel Herndon Klein, Francisco Espitia, Kenneth Daily, Michael Zeller, Pierre Baldi, Bogi Andersen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Acceso en liña:http://europepmc.org/articles/PMC3400561?pdf=render
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