Basal Serum Thyroxine Level should Guide Initial Thyroxine Replacement Dose in Neonates with Congenital Hypothyroidism

Objective:Initial high-dose sodium levothyroxine (Na-LT4) (10-15 μg/kg/day) replacement for primary congenital hypothyroidism (CH) is recommended in guidelines. However, high-dose Na-LT4 risks iatrogenic hyperthyroidism. The aim of this study was to investigate the normalizing effect of varying init...

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Main Authors: Ceren Günbey, Alev Özön, E. Nazlı Gönç, Ayfer Alikaşifoğlu, Sevilay Karahan, Nurgün Kandemir
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Endocrinology and Diabetes Society 2021-09-01
Colecção:JCRPE
Assuntos:
newborn screening
children
congenital hypothyroidism
na-l thyroxine
dose
Acesso em linha: http://www.jcrpe.org/archives/archive-detail/article-preview/basal-serum-thyroxine-level-should-guide-nitial-th/42983
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