Examination of the Efficacy and Cross-Reactivity of a Novel Polyclonal Antibody Targeting the Disintegrin Domain in SVMPs to Neutralize Snake Venom

Snake envenomation can result in hemorrhage, local necrosis, swelling, and if not treated properly can lead to adverse systemic effects such as coagulopathy, nephrotoxicity, neurotoxicity, and cardiotoxicity, which can result in death. As such, snake venom metalloproteinases (SVMPs) and disintegrins...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Shelby S. Szteiter, Ilse N. Diego, Jonathan Ortegon, Eliana M. Salinas, Abcde Cirilo, Armando Reyes, Oscar Sanchez, Montamas Suntravat, Emelyn Salazar, Elda E. Sánchez, Jacob A. Galan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-03-01
Schriftenreihe:	Toxins
Schlagworte:	<i>C. atrox</i> <i>C. o. helleri</i> antivenom disintegrin SVMP PII/PIII anti-disintegrin
Online-Zugang:	https://www.mdpi.com/2072-6651/13/4/254
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