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Hallmarks of human “immunosenescence”: adaptation or dysregulation?

<p>Abstract</p> <p>Is immunosenescence an intrinsic ageing process leading to dysregulation of immunity or an adaptive response of the individual to pathogen exposure? Age-associated differences in bone marrow immune cell output and thymic involution suggest the former. Accepted hallmarks of immunos...

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Autore principale: Pawelec Graham
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-07-01
Serie:Immunity & Ageing
Accesso online:http://www.immunityageing.com/content/9/1/15
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