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Differential Regulation of PIWI-LIKE 2 Expression in Primordial Germ Cell Tumor Cell Lines by Promoter Methylation

PIWI-LIKE 2, a member of the ARGONAUTE protein family, is exclusively expressed in pre-pachytene and pachytene stages of spermatogenesis. PIWI-LIKE 2 acts in the germ cell development and the silencing of retrotransponsons to maintain the genomic integrity and stem cell character. In the present stu...

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Hlavní autoři: Maria Giebler, Thomas Greither, Hermann M. Behre
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-09-01
Edice:Frontiers in Genetics
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On-line přístup:https://www.frontiersin.org/article/10.3389/fgene.2018.00375/full
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