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What’s on the menu?: metabolic constraints in the pancreatic tumor microenvironment

The tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) is composed of a dense stromal compartment and is poorly vascularized, resulting in limited nutrient delivery. As a result, PDAC cells must adapt to cope with the metabolic stresses brought on by TME nutrient limitation. In...

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Detaylı Bibliyografya
Asıl Yazarlar: Colin Sheehan, Alexander Muir
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2025-07-01
Seri Bilgileri:The Journal of Clinical Investigation
Online Erişim:https://doi.org/10.1172/JCI191940
Etiketler: Etiketle
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