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Stability-indicating method development and validation for the concurrent determination of darunavir, cobicistat, emtricitabine and tenofovir alafenamide by UPLC in bulk and tablet dosage forms

Abstract Background Tablet dosage forms containing combination of darunavir a protease inhibitor, cobicistat a cytochrome P450 3A inhibitor, emtricitabine and tenofovir alafenamide which were nucleoside reverse transcriptase inhibitors were approved by USFDA on 1st July 2018 to suppress the viral lo...

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Principais autores: M. Satya Venkata Sakuntala, A. Lakshmana Rao, M. William Carey
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2021-12-01
coleção:Future Journal of Pharmaceutical Sciences
Assuntos:
UPLC
Stability indicating
Tenofovir alafenamide
Cobicistat
Emtricitabine
Darunavir
Acesso em linha:https://doi.org/10.1186/s43094-021-00384-3
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