Identifying genetic determinants of outer retinal function in mice using a large-scale gene-targeted screen.

Electroretinography (ERG) provides a noninvasive functional measure of multiple cell types of the outer retina. We conducted an ERG-based screen of 530 single-gene knockout mouse strains generated as part of the International Mouse Phenotyping Consortium, representing 2.5% of all protein-coding gene...

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Detalles Bibliográficos

Principais autores:	Janine M Wotton, Mark P Krebs, Riccardo Sangermano, Jessica K Wong, Cynthia Smith, Amelia M Willett, Douglas Howell, Abby Jones, Catherine Witmeyer, Jacob P Lowy, Michael McFarland, Stephan A Murray, Robert E Braun, Patsy M Nishina, Eric A Pierce, Emily M Place, Kinga M Bujakowska, Neal S Peachey, Jacqueline K White
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2025-09-01
Series:	PLoS Genetics
Acceso en liña:	https://doi.org/10.1371/journal.pgen.1011886
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