A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.

Insufficient or dysregulated energy metabolism may underlie diverse inherited and degenerative diseases, cancer, and even aging itself. ATP is the central energy carrier in cells, but critical pathways for regulating ATP levels are not systematically understood. We combined a pooled clustered regula...

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Autors principals:	Bryce A Mendelsohn, Neal K Bennett, Maxwell A Darch, Katharine Yu, Mai K Nguyen, Daniela Pucciarelli, Maxine Nelson, Max A Horlbeck, Luke A Gilbert, William Hyun, Martin Kampmann, Jean L Nakamura, Ken Nakamura
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2018-08-01
Col·lecció:	PLoS Biology
Accés en línia:	http://europepmc.org/articles/PMC6110572?pdf=render
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