Effect of IL-10 Deficiency on TGFβ Expression during Fatal Alphavirus Encephalomyelitis in C57Bl/6 Mice

Sindbis virus (SINV) causes viral encephalitis in mice with strain-dependent virulence. Fatal encephalomyelitis in C57Bl/6 mice infected with a neuroadapted strain of SINV (NSV) is an immunopathogenic process that involves Th17 cells modulated by the regulatory cytokine IL-10. To further characteriz...

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Bibliografische Detailangaben

Hauptverfasser:	Nina M. Martin, Diane E. Griffin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-08-01
Schriftenreihe:	Viruses
Schlagworte:	neuroadapted Sindbis virus innate lymphoid cells inflammation transforming growth factor beta encephalomyelitis mice
Online-Zugang:	https://www.mdpi.com/1999-4915/14/8/1791
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