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A gene expression map of host immune response in human brucellosis

Brucellosis is a common zoonotic disease caused by intracellular pathogens of the genus Brucella. Brucella infects macrophages and evades clearance mechanisms, thus resulting in chronic parasitism. Herein, we studied the molecular changes that take place in human brucellosis both in vitro and ex viv...

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Principais autores: Ioannis Mitroulis, Akrivi Chrysanthopoulou, Georgios Divolis, Charalampos Ioannidis, Maria Ntinopoulou, Athanasios Tasis, Theocharis Konstantinidis, Christina Antoniadou, Natalia Soteriou, George Lallas, Stella Mitka, Mathias Lesche, Andreas Dahl, Stephanie Gembardt, Maria Panopoulou, Paschalis Sideras, Ben Wielockx, Ünal Coskun, Konstantinos Ritis, Panagiotis Skendros
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-08-01
coleção:Frontiers in Immunology
Assuntos:
brucellosis
immunity
transcriptomics
macrophages
polymorphonuclear neutrophils
peripheral blood mononuclear cells
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.951232/full
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