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The Impact of Metformin on the Development of Hypothyroidism and Cardiotoxicity Induced by Cyclophosphamide, Methotrexate, and Fluorouracil in Rats

Cyclophosphamide (CYP), methotrexate (MTX), and 5-fluorouracil (5-FU) are extensively utilized in the therapeutic management of various malignancies. It is noteworthy, however, that potential chemotherapy-related complications include the occurrence of hypothyroidism and cardiotoxicity. Metformin (M...

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Autori principali: Ahmad H. Alhowail, Maha A. Aldubayan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2023-09-01
Serie:Pharmaceuticals
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Accesso online:https://www.mdpi.com/1424-8247/16/9/1312
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