The MTR A2756G polymorphism is associated with an increase of plasma homocysteine concentration in Brazilian individuals with Down syndrome

Individuals with Down syndrome (DS) present decreased homocysteine (Hcy) concentration, reflecting a functional folate deficiency secondary to overexpression of the cystathionine ß-synthase gene. Since plasma Hcy may be influenced by genetic polymorphisms, we evaluated the influence of C677T and A12...

Popoln opis

Bibliografske podrobnosti

Principais autores:	J.M Biselli, E.M Goloni-Bertollo, R Haddad, M.N Eberlin, E.C Pavarino-Bertelli
Format:	Artigo
Jezik:	Inglês
Izdano:	Associação Brasileira de Divulgação Científica 2008-01-01
Serija:	Brazilian Journal of Medical and Biological Research
Teme:	Down syndrome Trisomy 21 Polymorphism Homocysteine Mass spectrometry (LC-MS/MS)
Online dostop:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000100006
Oznake:	Označite Brez oznak, prvi označite!