Structural and Computational Insights into Transketolase-like 1 (TKTL-1): Distinction from TKT and Implications for Cancer Metabolism and Therapeutic Targeting

Transketolase-like protein 1 (TKTL-1) has been implicated in altered cancer metabolism, yet its structure and molecular function remain poorly understood. In this study, we established a homology model of TKTL-1 using multiple templates and validated it through sequence alignment and structural comp...

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Principais autores:	Ahmad Junaid, Caleb J. Nwaogwugwu, Sameh H. Abdelwahed
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-09-01
coleção:	Molecules
Assuntos:	TKTL-1 cancer metabolism transketolase pentose phosphate pathway therapeutic targeting computational analysis
Acesso em linha:	https://www.mdpi.com/1420-3049/30/19/3905
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