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A novel SATB1 protein isoform with different biophysical properties

Intra-thymic T cell development is coordinated by the regulatory actions of SATB1 genome organizer. In this report, we show that SATB1 is involved in the regulation of transcription and splicing, both of which displayed deregulation in Satb1 knockout murine thymocytes. More importantly, we character...

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Principais autores: Tomas Zelenka, Dionysios-Alexandros Papamatheakis, Petros Tzerpos, Giorgos Panagopoulos, Konstantinos C. Tsolis, Vassilis M. Papadakis, Dimitris Mariatos Metaxas, George Papadogkonas, Eleftherios Mores, Manouela Kapsetaki, Joseph Papamatheakis, David Stanek, Charalampos Spilianakis
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2023-08-01
סדרה:Frontiers in Cell and Developmental Biology
נושאים:
SATB1
T cells
chromatin organization
prion
phase separation
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fcell.2023.1242481/full
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