Copper–zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma
Multiple myeloma (MM) is an incurable B-cell malignancy. The proteasome inhibitor bortezomib (BTZ) is a frontline MM drug; however, intrinsic or acquired resistance to BTZ remains a clinical hurdle. As BTZ induces oxidative stress in MM cells, we queried if altered redox homeostasis promotes BTZ res...
Furkejuvvon:
| Váldodahkkit: | , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Elsevier
2015-04-01
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| Ráidu: | Redox Biology |
| Fáttát: | |
| Liŋkkat: | http://www.sciencedirect.com/science/article/pii/S2213231714001141 |
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