DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling.

Remodeling of the extracellular matrix (ECM) in the tumor microenvironment promotes glioma progression. Chondroitin sulfate (CS) proteoglycans appear in the ECM and on the cell surface, and can be catalyzed by dermatan sulfate epimerase to form chondroitin sulfate/dermatan sulfate (CS/DS) hybrid cha...

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Autors principals:	Wen-Chieh Liao, Chih-Kai Liao, You-Huan Tsai, To-Jung Tseng, Li-Ching Chuang, Chyn-Tair Lan, Hung-Ming Chang, Chiung-Hui Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2018-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC5986151?pdf=render
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