Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans

Chromoanasynthesis is a recently discovered phenomenon in humans with congenital diseases that is characterized by complex genomic rearrangements (CGRs) resulting from aberrant repair of catastrophic chromosomal damage. How these CGRs are induced is not known. Here, we describe the structure and fun...

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Principais autores:	Omar A. Itani, Stephane Flibotte, Kathleen J. Dumas, Donald G. Moerman, Patrick J. Hu
格式:	Artigo
語言:	Inglês
出版:	Oxford University Press 2016-02-01
叢編:	G3: Genes, Genomes, Genetics
主題:	chromoanasynthesis chromothripsis C. elegans insulin-like growth factor signaling dauer
在線閱讀:	http://g3journal.org/lookup/doi/10.1534/g3.115.024257
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