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Decoding the distribution of glycan receptors for human-adapted influenza A viruses in ferret respiratory tract.

Ferrets are widely used as animal models for studying influenza A viral pathogenesis and transmissibility. Human-adapted influenza A viruses primarily target the upper respiratory tract in humans (infection of the lower respiratory tract is observed less frequently), while in ferrets, upon intranasa...

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Auteurs principaux: Akila Jayaraman, Aarthi Chandrasekaran, Karthik Viswanathan, Rahul Raman, James G Fox, Ram Sasisekharan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2012-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3281014?pdf=render
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